A native of Vancouver, Katharine Isabelle began acting at an early age. Her big screen debut came in Joel Schumacher’s critical success, "Cousins," starring Ted Danson and Isabella Rossellini, as Rossellini’s daughter.
Memorable guest appearances in such television series as "The X-Files," "DaVinci’s Inquest," "Smallville" and "Supernatural" followed. American audiences began to take notice of Isabelle after her performance in the teen thriller, "Disturbing Behavior," and a memorable turn opposite Al Pacino in Christopher Nolan’s suspense hit, "Insomnia."
However, it would be her starring role as "Ginger" in "Ginger Snaps" and its lucrative indie hit sequels that would give her cult status among genre fans. Isabelle is also a hot commodity on the independent film scene as well, with starring roles in such films as "Falling Angels," "On The Corner" and "Turning Paige."
In 2008, Isabelle was the recipient of the Gemini Award for Best Performance by an Actress in a Featured Supporting Role in a Dramatic Program or Mini-Series for her role in "The Englishman’s Boy." Most recently, she was a series regular on the Showtime series "Endgame," which earned her a 2011 Gemini Nomination for Best Performance by an Actress in a Featured Supporting Role in a Dramatic Series.